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Ritonavir or lopinavir/ritonavir significantly boost plasma concentrations of oxycodone in healthful human volunteers due to inhibition of CYP3A4 and CYP2D6.[fifty eight] Rifampicin greatly reduces plasma concentrations of oxycodone because of sturdy induction of CYP3A4.After some time, your body could rely on the medication to function. For those

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